Protein corona formed in the gastrointestinal tract and its impacts on oral delivery of nanoparticles

The interaction of nanoparticles (NPs) with proteins and the formation of protein corona in the biological fluids are of great interest and significance for drug delivery. In the past decade, the corona formation in the blood and its impacts on the in vitro and in vivo fate of NPs has been well investigated and reviewed. Recently, more and more attention is paid to the nano–protein interactions taking place in the gastrointestinal tract (GIT)...