Review paper
Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes
Abstract
Mitochondria are controlled by the coordination of two genomes: the mitochondrial and the nuclear DNA. As such, variations in nuclear gene expression as a consequence of mutations and epigenetic modifications can affect mitochondrial functionality. Conversely, the opposite could also be true. However, the relationship between mitochondrial dysfunction and epigenetics, such as nuclear DNA methylation, remains largely unexplored. Mitochondria...
Paper Details
Title
Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes
Published Date
Nov 23, 2020
Journal
Volume
12
Issue
1