Review paper
Developments in Carbohydrate-Based Metzincin Inhibitors
Abstract
Matrix metalloproteinases (MMPs) and A disintegrin and Metalloproteinase (ADAMs) are zinc-dependent endopeptidases belonging to the metzincin superfamily. Upregulation of metzincin activity is a major feature in many serious pathologies such as cancer, inflammations, and infections. In the last decades, many classes of small molecules have been developed directed to inhibit these enzymes. The principal shortcomings that have hindered clinical...
Paper Details
Title
Developments in Carbohydrate-Based Metzincin Inhibitors
Published Date
Nov 10, 2020
Journal
Volume
13
Issue
11
Pages
376 - 376
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