Role of miRNAs in Sigmoid Colon Cancer: A Search for Potential Biomarkers

Diego Marques; Layse Raynara Ferreira-Costa; Lorenna Larissa Ferreira-Costa; Ana Beatriz Bezerra-Oliveira; Romualdo da Silva Correa; Carlos Cesar de Oliveira Ramos; Tatiana Vinasco-Sandoval; Katia de Paiva Lopes; Ricardo Assunção Vialle; Amanda Ferreira Vidal; Vivian Nogueira Silbiger; Ândrea Ribeiro-dos-Santos

doi:https://doi.org/10.3390/cancers12113311

doi.org/10.3390/cancers12113311

Role of miRNAs in Sigmoid Colon Cancer: A Search for Potential Biomarkers

Diego Marques

5

,

Layse Raynara Ferreira-Costa

2

,

..., Ândrea Ribeiro-dos-Santos

24

Cancers5.20

Volume: 12, Issue: 11, Pages: 3311 - 3311

Published: Nov 10, 2020

Abstract

The aberrant expression of microRNAs in known to play a crucial role in carcinogenesis. Here, we evaluated the miRNA expression profile of sigmoid colon cancer (SCC) compared to adjacent-to-tumor (ADJ) and sigmoid colon healthy (SCH) tissues obtained from colon biopsy extracted from Brazilian patients. Comparisons were performed between each group separately, considering as significant p-values < 0.05 and |Log2(Fold-Change)| > 2. We found...

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Paper Details

Title

Role of miRNAs in Sigmoid Colon Cancer: A Search for Potential Biomarkers

DOI

doi.org/10.3390/cancers12113311

Published Date

Nov 10, 2020

Journal

Cancers

Volume

12

Issue

11

Pages

3311 - 3311

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