Original paper
Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Abstract
Cisplatin is currently used to treat inoperable recurrent meningiomas, but its side effects and drug resistance limit its use. Metformin has recently been identified as a chemosensitizing agent. However, the combined treatment of cisplatin and metformin in high-grade meningiomas has not been reported. Herein, our findings demonstrate metformin significantly enhanced cisplatin-induced inhibition of proliferation in meningioma cells, which was...
Paper Details
Title
Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Published Date
Mar 1, 2021
Volume
20
Pages
119 - 131
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Notes
History