Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits
Abstract
Background Buprenorphine is one of the most used analgesics for postoperative pain in rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for intravenous (IV), intramuscular (IM), and subcutaneous (SC) administration, despite lack of pharmacokinetic data. Five male and five female New Zealand White rabbits (mean ± SD body weight 3.1 ± 0.3 kg) were administered 0.05 mg/kg buprenorphine by the IV, IM and SC routes and 0.1 mg/kg...
Paper Details
Title
Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits
Published Date
Nov 11, 2020
Journal
Volume
16
Issue
1
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