The double-edged sword of H19 lncRNA: Insights into cancer therapy
Abstract
H19 long non-coding RNA (lncRNA) has many functions in cancer. Some studies have reported that H19 acts as an oncogene and is involved in cancer progression by activating epithelial-mesenchymal transition (EMT), the cell cycle and angiogenesis via mechanisms like microRNA (miRNA) sponging – the binding to and inhibition of miRNA activity. This makes H19 lncRNA a potential target for cancer therapeutics. However, several conflicting studies have...
Paper Details
Title
The double-edged sword of H19 lncRNA: Insights into cancer therapy
Published Date
Mar 1, 2021
Journal
Volume
500
Pages
253 - 262
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