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Review paper

Molecular and cellular mechanisms of liver fibrosis and its regression

Volume: 18, Issue: 3, Pages: 151 - 166
Published: Oct 30, 2020
Abstract
Chronic liver injury leads to liver inflammation and fibrosis, through which activated myofibroblasts in the liver secrete extracellular matrix proteins that generate the fibrous scar. The primary source of these myofibroblasts are the resident hepatic stellate cells. Clinical and experimental liver fibrosis regresses when the causative agent is removed, which is associated with the elimination of these activated myofibroblasts and resorption of...
Paper Details
Title
Molecular and cellular mechanisms of liver fibrosis and its regression
Published Date
Oct 30, 2020
Volume
18
Issue
3
Pages
151 - 166
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