Original paper
Taxane-induced Attenuation of the CXCR2/BCL-2 Axis Sensitizes Prostate Cancer to Platinum-based Treatment
Abstract
Taxanes are the most active chemotherapy agents in metastatic castration-resistant prostate cancer (mCRPC) patients; yet, resistance occurs almost invariably, representing an important clinical challenge. Taxane-platinum combinations have shown clinical benefit in a subset of patients, but the mechanistic basis and biomarkers remain elusive.To identify mechanisms and response indicators for the antitumor efficacy of taxane-platinum combinations...
Paper Details
Title
Taxane-induced Attenuation of the CXCR2/BCL-2 Axis Sensitizes Prostate Cancer to Platinum-based Treatment
Published Date
Jun 1, 2021
Journal
Volume
79
Issue
6
Pages
722 - 733
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Notes
History