An investigation of the antidepressant‐like effect of Jiaotaiwan in rats by nontargeted metabolomics based on ultra‐high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry

Depression is a mental disorder characterized by persistent unhappiness, lack of interest, with cognitive and sleep disorders. Jiaotaiwan is a traditional Chinese medicine for the treatment of insomnia and depressive‐like symptoms. In this study, the major chemical components in Jiaotaiwan were qualitatively analyzed using ultra high performance liquid chromatography quadrupole time‐of‐flight mass spectrometry, and a model of depression in rats...