White Matter Integrity According to the Stage of Mental Disorder in Youth

The present study investigated differences in white matter (WM) integrity between 96 young people with affective and/or psychotic symptoms classified at an early stage of mental disorder (i.e. ‘attenuated syndrome’; stage 1b), 85 young people classified at a more advanced stage of mental disorder (i.e. ‘discrete disorder’; stage 2), and 81 demographically matched healthy controls using diffusion tensor imaging. The relationship between WM...