Original paper
Cancer immunotherapy via targeted TGF-β signalling blockade in TH cells
Abstract
Cancer arises from malignant cells that exist in dynamic multilevel interactions with the host tissue. Cancer therapies aiming to directly kill cancer cells, including oncogene-targeted therapy and immune-checkpoint therapy that revives tumour-reactive cytotoxic T lymphocytes, are effective in some patients1,2, but acquired resistance frequently develops3,4. An alternative therapeutic strategy aims to rectify the host tissue pathology, including...
Paper Details
Title
Cancer immunotherapy via targeted TGF-β signalling blockade in TH cells
Published Date
Oct 21, 2020
Journal
Volume
587
Issue
7832
Pages
121 - 125
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Notes
History