Second primary neoplasms in patients with lung and gastroenteropancreatic neuroendocrine neoplasms: Data from a retrospective multi-centric study

Patients with sporadic neuroendocrine neoplasms may exhibit a higher risk of a second primary tumor than the general population.This study aimed to analyze the occurrence of second primary malignancies.A retrospective cohort of 2757 patients with sporadic lung and gastro-entero-pancreatic neuroendocrine neoplasms, managed at eight Italian tertiary referral Centers, was included.Between 2000 and 2019, a second primary malignancy was observed in...