Prognostic Implications Of Metabolic Phenotype: The Role Of FDG-PET/CT In Predicting Immunotherapy Efficacy In Recurrent/Metastatic Head And Neck Cancer

Immunotherapy has emerged as a novel treatment modality for recurrent/metastatic head and neck cancer (R/M HNC) patients, although overall survival remains poor. Given the reliance of immunotherapy on circulating immune cells, we hypothesized that metabolic signatures of nontumoral hematopoietic tissues derived from quantitative analysis of pre-treatment 18-fluorodeoxyglucose-positron emission tomography-computed tomography (PET/CT) could aid in...