Effects of Nonporous Silica Nanoparticles on Human Trabecular Meshwork Cells

Precis null Silica nanoparticles, which are potential drug carriers for glaucoma treatment, may induce mild dose-dependent cytotoxicity but not so severe as to compromise a mammalian target of rapamycin pathway in immortalized trabecular meshwork cells. null Purpose null Nanoparticle-based ophthalmic drug delivery is a promising field of drug development. In this study, we evaluated the effect of nonporous silica nanoparticles (SiNPs) on human...