Choul Yong Park
Dongguk University
CytotoxicityOphthalmologyOptometryOpticsBiophysicsSurgeryPathologyMolecular biologyChemistryImmunologyKeratometerIn vivoDioptreCataract surgeryCorneaVisual acuityOptical coherence tomographyLacrimal glandPhacoemulsificationNitric oxideMedicineBiology
90Publications
18H-index
878Citations
Publications 85
Newest
#1Sang Hyeok Lee (Dongguk University)
#2Martha Kim (Dongguk University)H-Index: 9
Last. Choul Yong Park (Dongguk University)H-Index: 18
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The effect of small anisometropia on visual fatigue when using virtual reality (VR) devices was investigated. Participants (n = 34) visited three times. In the first visit, VR exposure (10 minutes) was conducted with the full correction of the refractive error of both eyes. Experimental anisometropia was induced by adding a +1.0 diopter spherical lens either on the dominant eyes in the second visit or on the non-dominant eyes in the third visit. At each visit, the participants played a predeterm...
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#2Choul Yong ParkH-Index: 18
Last. Minwook ChangH-Index: 12
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#1Kang Min Lee (Dongguk University)
#2Choul Yong Park (Dongguk University)H-Index: 18
Last. Martha Kim (Dongguk University)H-Index: 9
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#1Joo Hee Park (Dongguk University)H-Index: 8
#2Martha Kim (Dongguk University)H-Index: 9
Last. Choul Yong Park (Dongguk University)H-Index: 18
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Nitric oxide (NO) has the potential to modulate myofibroblast differentiation. In this study, we investigated the effect of exogenous NO on the myofibroblast differentiation of human keratocytes using sodium nitrite as a NO donor. Myofibroblasts were induced by exposing resting keratocytes to transforming growth factor (TGF)-β1. N-cadherin and α-smooth muscle actin (αSMA) were used as myofibroblast markers. Both resting keratocytes and -stimulated keratocytes were exposed to various concentratio...
1 CitationsSource
#1Joo Hee Park (Dongguk University)H-Index: 8
#2Martha Kim (Dongguk University)H-Index: 9
Last. Choul Yong Park (Dongguk University)H-Index: 18
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Moxifloxacin hydrochloride (MXF) is widely used for the prevention of bacterial endophthalmitis after intraocular surgeries. However, the safety issue of intracameral injection of MXF for human corneal endothelial cells (HCECs) is still debatable. In this study, we investigated concentration-dependent cytotoxicity (0.05-1 mg/ml) of MXF for immortalized HCECs (B4G12 cell) and the underlying mechanism. Reactive oxygen generation (ROS) and cell viability after MXF exposure was measured. Flow cytome...
1 CitationsSource
#1Martha Kim (Dongguk University)H-Index: 9
#2Joo Hee Park (Dongguk University)H-Index: 8
Last. Choul Yong Park (Dongguk University)H-Index: 18
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Precis Silica nanoparticles, which are potential drug carriers for glaucoma treatment, may induce mild dose-dependent cytotoxicity but not so severe as to compromise a mammalian target of rapamycin pathway in immortalized trabecular meshwork cells. Purpose Nanoparticle-based ophthalmic drug delivery is a promising field of drug development. In this study, we evaluated the effect of nonporous silica nanoparticles (SiNPs) on human trabecular meshwork (TM) cells. Methods TM cells were exposed to di...
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#1Dong Ju Kim (Dongguk University)H-Index: 3
#2Mi-Young Jung (Dongguk University)
Last. Choul Yong Park (Dongguk University)H-Index: 18
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Ocular surface diseases (OSD) can cause serious visual deterioration and discomfort. Commercial artificial tear solution containing hyaluronic acid (HA) show excellent biocompatibility and unique viscoelastic characteristics. Here, we developed a novel HA membrane (HAM) by chemical crosslinking using 1,4-butanediol diglycidyl ether for the effective treatment of OSDs. The main purpose of HAMs is to provide sustained release of HA to modulate the wound healing response in OSDs. The safety and eff...
1 CitationsSource
#1Su Jin Kim (PNU: Pusan National University)H-Index: 2
#2Seung Uk Lee (Kosin University)H-Index: 6
Last. Ji Eun Lee (PNU: Pusan National University)H-Index: 19
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BACKGROUND We report a case of atypical presentation of IgG4-related disease (IgG4-RD) with recurrent scleritis and optic nerve involvement. CASE PRESENTATION A 61-year-old male presented with ocular pain and injection in his left eye for 2 months. Ocular examination together with ancillary testing led to the diagnosis of scleritis, which relapsed in spite of several courses of steroid treatment. After cessation of steroid, the patient complained of severe retro-orbital pain and blurred vision. ...
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#1Soo Hyun Park (Inha University)H-Index: 3
#2Choul Yong Park (Dongguk University)H-Index: 18
Last. Nam-Hee Kim (Dongguk University)H-Index: 5
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Optic neuritis (ON) has been considered to be an important factor in the diagnosis of multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), making ON detection increasingly critical for early diagnosis. Furthermore, subclinical ONs presenting no distinct decrease in visual acuity can be missed. Low contrast visual acuity (LC-VA) are known to be able to capture visual loss not seen in conventional high-contrast visual acuity (HC-VA) in MS. Therefore, to increase the sensitiv...
1 CitationsSource
#1Su Hwan Park (PNU: Pusan National University)H-Index: 2
#2Chengye Che (Qingdao University)H-Index: 15
Last. Ji Eun Lee (PNU: Pusan National University)H-Index: 19
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Aim To compare the clinical results of femtosecond (FS) laser in situ keratomileusis (LASIK) in high myopic patients and low myopic patients. Methods This study included 212 myopic eyes undergoing LASIK using a VisuMax 500kHz FS laser. All treated eyes were assigned to one of two groups according to preoperative manifest spherical refraction: low myopia group (A, >-4.0 D) and high myopia group (B, ≤-4.0 D). Uncorrected and corrected distance visual acuity (UDVA, CDVA), refractive errors, and hig...
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