Self‐reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time‐dependent progression

Introduction Obstructive sleep apnea (OSA) is associated with Alzheimer's disease (AD) biomarkers in cognitively normal (CN) and mild cognitive impaired (MCI) participants. However, independent and combined effects of OSA, amyloid beta (Aβ) and tau‐accumulation on AD time‐dependent progression risk is unclear. Methods Study participants grouped by biomarker profile, as described by the A/T/N scheme, where “A” refers to aggregated Aβ, “T”...