Original paper
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase
Abstract
Lung cancer is the leading cause of cancer-related mortality and causes more than a million deaths per year. Gefitinib is the first-line agent of advanced lung cancer, however, resistance to gefitinib becomes a major problem in clinical application. Transketolase (TKT) is a key enzyme functioning between the oxidative arm and the non-oxidative arm of the pentose phosphate pathway. In this study, we firstly found that the expression of TKT was...
Paper Details
Title
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase
Published Date
Jan 1, 2021
Volume
890
Pages
173647 - 173647
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Notes
History