Metabolic precision labeling enables selective probing of O-linked N -acetylgalactosamine glycosylation

Volume: 117, Issue: 41, Pages: 25293 - 25301
Published: Sep 28, 2020
Abstract
Protein glycosylation events that happen early in the secretory pathway are often dysregulated during tumorigenesis. These events can be probed, in principle, by monosaccharides with bioorthogonal tags that would ideally be specific for distinct glycan subtypes. However, metabolic interconversion into other monosaccharides drastically reduces such specificity in the living cell. Here, we use a structure-based design process to develop the...
Paper Details
Title
Metabolic precision labeling enables selective probing of O-linked N -acetylgalactosamine glycosylation
Published Date
Sep 28, 2020
Volume
117
Issue
41
Pages
25293 - 25301
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.