Mycobacterium tuberculosis progresses through two phases of latent infection in humans
Abstract
Little is known about the physiology of latent Mycobacterium tuberculosis infection. We studied the mutational rates of 24 index tuberculosis (TB) cases and their latently infected household contacts who developed active TB up to 5.25 years later, as an indication of bacterial physiological state and possible generation times during latent TB infection in humans. Here we report that the rate of new mutations in the M. tuberculosis genome decline...
Paper Details
Title
Mycobacterium tuberculosis progresses through two phases of latent infection in humans
Published Date
Sep 25, 2020
Journal
Volume
11
Issue
1
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