Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits

Objective Current understanding of the neuromodulatory effects of deep brain stimulation (DBS) on large‐scale brain networks remains elusive, largely due to the lack of techniques that can reveal DBS‐induced activity at the whole‐brain level. Using a novel 3T magnetic resonance imaging (MRI)‐compatible stimulator, we investigated whole‐brain effects of subthalamic nucleus (STN) stimulation in patients with Parkinson disease. Methods Fourteen...