Annals of Neurology
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#1Carlo W CeredaH-Index: 15
#2Giovanni BiancoH-Index: 2
Last. Jeremy J Heit (SU: Stanford University)H-Index: 23
view all 19 authors...
OBJECTIVE Perfusion imaging identifies anterior circulation stroke patients who respond favorably to endovascular thrombectomy (ET), but its role in basilar artery occlusion (BAO) is unknown. We hypothesized that BAO patients with limited regions of severe hypoperfusion (time to reach maximum concentration in seconds [Tmax] > 10) would have a favorable response to ET compared to patients with more extensive regions involved. METHODS We performed a multicenter retrospective cohort study of BAO pa...
#1Megan B. Richie (UCSF: University of California, San Francisco)H-Index: 7
#2Adeline Goss (AHS: Alameda Health System)
Last. Safwan Jaradeh (SU: Stanford University)H-Index: 26
view all 3 authors...
#1Shixiong Lei (Zhengzhou University)
#2Yan Hu (Zhengzhou University)
Last. Fuyou Guo (Zhengzhou University)H-Index: 9
view all 4 authors...
#1Manu E. Jokela (University of Turku)H-Index: 1
#2Jari Karhu (TYKS: Turku University Hospital)H-Index: 3
Last. Mika H. Martikainen (University of Turku)H-Index: 13
view all 4 authors...
#1Cathy Meng Fei Li (UWO: Western University)H-Index: 1
#2Jonathan Romsa (UWO: Western University)H-Index: 5
Last. J. Alexander Fraser (UWO: Western University)H-Index: 8
view all 4 authors...
#1Amanda C. Y. Chan (University Health System)H-Index: 3
#2Hiu Yi Wong (HKUST: Hong Kong University of Science and Technology)
Last. Anselm Mak (University Health System)H-Index: 33
view all 21 authors...
Objective null Small fiber neuropathy (SFN) is clinically and etiologically heterogeneous. While autoimmunity has been postulated to be pathophysiologically important in SFN, few autoantibodies have been described. We aimed to identify autoantibodies associated with idiopathic SFN (iSFN) by a novel high-throughput protein microarray platform that captures autoantibodies expressed in native conformational state. null Methods null Sera from 58 SFN patients and 20 age- and gender-matched healthy co...
#1Alexandros Polymeris (University of Basel)H-Index: 14
#2Kosmas Macha (FAU: University of Erlangen-Nuremberg)H-Index: 7
view all 43 authors...
OBJECTIVE To investigate the safety and effectiveness of direct oral anticoagulants (DOAC) versus vitamin K antagonists (VKA) after recent stroke in patients with atrial fibrillation (AF) aged ≥85 years. METHODS Individual patient data analysis from seven prospective stroke cohorts. We compared DOAC versus VKA treatment among patients with AF and recent stroke (<3 months) aged ≥85 versus <85 years. Primary outcome was the composite of recurrent stroke, intracranial hemorrhage (ICH) and all-cause...
#1Carlo Wilke (University of Tübingen)H-Index: 15
#2Selina Reich (University of Tübingen)H-Index: 7
Last. Matthis Synofzik (University of Tübingen)H-Index: 57
view all 33 authors...
Objective null While the presymptomatic stages of frontotemporal dementia (FTD) provide a unique chance to delay or even prevent neurodegeneration by early intervention, they remain poorly defined. Leveraging a large multicentre cohort of genetic FTD mutation carriers, we provide a biomarker-based stratification and biomarker cascade of the likely most treatment-relevant stage within the presymptomatic phase: the conversion stage. null Methods null We longitudinally assessed serum levels of neur...
#1Cindy Bokobza (University of Paris)H-Index: 5
#2Pooja Joshi (University of Paris)
Last. Juliette Van Steenwinckel (University of Paris)H-Index: 20
view all 17 authors...
Objectives null In the premature newborn, perinatal inflammation mediated by microglia contributes significantly to neurodevelopmental injuries including white matter injury (WMI). Brain inflammation alters development through neuroinflammatory processes mediated by activation of homeostatic microglia toward a pro-inflammatory and neurotoxic phenotype. Investigating immune regulators of microglial activation is crucial to find effective strategies to prevent and treat WMI. null Methods null Ex v...
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