Original paper
Sex-Specific Genetic Associations for Barrett’s Esophagus and Esophageal Adenocarcinoma
Abstract
Background & AimsEsophageal adenocarcinoma (EA) and its premalignant lesion, Barrett’s esophagus (BE), are characterized by a strong and yet unexplained male predominance (with a male-to-female ratio in EA incidence of up to 6:1). Genome-wide association studies (GWAS) have identified more than 20 susceptibility loci for these conditions. However, potential sex differences in genetic associations with BE/EA remain largely unexplored.MethodsGiven...
Paper Details
Title
Sex-Specific Genetic Associations for Barrett’s Esophagus and Esophageal Adenocarcinoma
Published Date
Dec 1, 2020
Journal
Volume
159
Issue
6
Pages
2065 - 2076.e1
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Notes
History