In-cell architecture of the nuclear pore and snapshots of its turnover

Nature64.80
Volume: 586, Issue: 7831, Pages: 796 - 800
Published: Sep 2, 2020
Abstract
Nuclear pore complexes (NPCs) fuse the inner and outer membranes of the nuclear envelope. They comprise hundreds of nucleoporins (Nups) that assemble into multiple subcomplexes and form large central channels for nucleocytoplasmic exchange1,2. How this architecture facilitates messenger RNA export, NPC biogenesis and turnover remains poorly understood. Here we combine in situ structural biology and integrative modelling with correlative light...
Paper Details
Title
In-cell architecture of the nuclear pore and snapshots of its turnover
Published Date
Sep 2, 2020
Journal
Volume
586
Issue
7831
Pages
796 - 800
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