Self‐Folding 3D Silk Biomaterial Rolls to Facilitate Axon and Bone Regeneration

Biomaterial scaffold designs are needed for self‐organizing features related to tissue formation while also simplifying the fabrication processes involved. Toward this goal, silk protein‐based self‐folding scaffolds to support 3D cell culture, while providing directional guidance and promotion of cell growth and differentiation, are reported. A simple and robust one‐step self‐folding approach is developed using bilayers consisting of a hydrogel...