Decreased frequency of allergy in juvenile idiopathic arthritis: Results of a case-control study.

Published on May 4, 2021in Modern Rheumatology2.113
· DOI :10.1080/14397595.2020.1812820
Pınar Özge Avar-Aydın (Istanbul University), Serdar Nepesov5
Estimated H-index: 5
(Istanbul University)
+ 4 AuthorsOzgur Kasapcopur35
Estimated H-index: 35
(Istanbul University)
To determine the frequency of Th2-mediated allergic diseases (AD) in mainly Th1-driven juvenile idiopathic arthritis (JIA) subtypes. Ninety-nine JIA patients and 128 control subjects were enrolled ...
#1Julia Matthias (TUM: Technische Universität München)
#1Julia Matthias (LMU: Ludwig Maximilian University of Munich)H-Index: 3
Last. Christina E. Zielinski (TUM: Technische Universität München)H-Index: 16
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: Th2 cells have evolved to protect from large helminth infections and to exert tissue protective functions in response to nonmicrobial noxious stimuli. The initiation, maintenance, and execution of these functions depend on the integration of diverse polarizing cues by cellular sensors and molecular programs as well as the collaboration with cells that are coopted for signal exchange. The complexity of input signals and cellular collaboration generates tissue specific Th2 cell heterogeneity and...
5 CitationsSource
#1Natalie J. Shiff (UF: University of Florida)H-Index: 15
#2Kiem Oen (UM: University of Manitoba)H-Index: 25
Last. Lisa M. Lix (UM: University of Manitoba)H-Index: 69
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OBJECTIVE:To estimate the incidence and prevalence of juvenile idiopathic arthritis (JIA) in children ages <16 years in the province of Manitoba, Canada, and to determine changes in estimates between 2000 and 2012. METHODS:JIA cases were ascertained from the administrative health data of Manitoba, using a validated case-finding algorithm. Annual incidence and prevalence rates were estimated using a generalized linear model with generalized estimating equations (GEEs), adjusting for sociodemograp...
5 CitationsSource
#1Gabriel Horta-Baas (Mexican Social Security Institute)H-Index: 5
#2María del Socorro Romero-Figueroa (Mexican Social Security Institute)H-Index: 7
AIM: Current studies demonstrate red blood cell distribution width (RDW) as a possible surrogate biomarker of inflammation. The objectives of the present study were to examine RDW in patients with osteoarthritis (OA), fibromyalgia (FM), rheumatoid arthritis (RA) and spondyloarthritis (SpA) and to evaluate its clinical importance. METHODS: Six hundred and ninety-nine ambulatory patients were evaluated. RDW, hemoglobin, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were assesse...
5 CitationsSource
#1Allison A. ThromH-Index: 2
#2Halima MoncrieffeH-Index: 15
Last. Anthony R. FrenchH-Index: 29
view all 14 authors...
: Polyarticular juvenile idiopathic arthritis (JIA) is among the most challenging of the JIA subtypes to treat. Even with current biologic therapies, the disease remains difficult to control in a substantial subset of patients, highlighting the need for new therapies. The aim of this study was to use the high dimensionality afforded by mass cytometry with phospho-specific antibodies to delineate signaling abnormalities in immune cells from treatment-naive polyarticular JIA patients. Peripheral b...
8 CitationsSource
#1Laura A. McIntosh (Cincinnati Children's Hospital Medical Center)H-Index: 1
#2Miranda C. Marion (Wake Forest University)H-Index: 26
Last. Susan D. Thompson (Cincinnati Children's Hospital Medical Center)H-Index: 51
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Objective Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and has a strong genomic component. To date, JIA genetic association studies have had limited sample sizes, used heterogeneous patient populations, or included only candidate regions. The aim of this study was to identify new associations between JIA patients with oligoarticular disease and those with IgM rheumatoid factor (RF)−negative polyarticular disease, which are clinically similar and the most pre...
25 CitationsSource
#1Kenan Barut (Istanbul University)H-Index: 16
#2Amra Adrovic (Istanbul University)H-Index: 13
Last. Ozgur Kasapcopur (Istanbul University)H-Index: 35
view all 4 authors...
Juvenile idiopathic arthritis is the most common chronic rheumatic disease of unknown aetiology in childhood and predominantly presents with peripheral arthritis. The disease is divided into several subgroups, according to demographic characteristics, clinical features, treatment modalities and disease prognosis. Systemic juvenile idiopathic arthritis, which is one of the most frequent disease subtypes, is characterized by recurrent fever and rash. Oligoarticular juvenile idiopathic arthritis, c...
35 CitationsSource
#1Lara J. Akinbami (CDC: Centers for Disease Control and Prevention)H-Index: 7
#2Alan E. Simon (CDC: Centers for Disease Control and Prevention)H-Index: 21
Last. Kenneth C. SchoendorfH-Index: 36
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AbstractObjectives: Children with asthma and allergies—particularly food and/or multiple allergies–are at risk for adverse asthma outcomes. This analysis describes allergy prevalence trends among US children by asthma status. Methods: We analyzed 2001–2013 National Health Interview Survey data for children aged 0–17 years. We estimated trends for reported respiratory, food, and skin allergy and the percentage of children with one, two, or all three allergy types by asthma status. We estimated un...
28 CitationsSource
#1Francisco A. Bonilla (Boston Children's Hospital)H-Index: 40
#2Isil B. Barlan (Marmara University)H-Index: 31
Last. Klaus Warnatz (University Medical Center Freiburg)H-Index: 65
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Francisco A. Bonilla, MD, PhD, Isil Barlan, MD, Helen Chapel, MD, Beatriz T. Costa-Carvalho, MD, Charlotte Cunningham-Rundles, MD, PhD, M. Teresa de la Morena, MD, Francisco J. Espinosa-Rosales, MD, Lennart Hammarstrom, MD, PhD, Shigeaki Nonoyama, MD, Isabella Quinti, MD, PhD, John M. Routes, MD, Mimi L.K. Tang, MD, PhD, and Klaus Warnatz, MD Boston, Mass; Istanbul, Turkey; Oxford, United Kingdom; Sao Paulo, Brazil; New York, NY; Dallas, Texas; Mexico City, Mexico; Stockholm, Sweden; Saitama, Ja...
323 CitationsSource
The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for establishing the "Practice parameter for the diagnosis and management of primary immunodeficiency." This is a complete and comprehensive document at the current time. The medical environment is a changing environment, and not all recommendations will be appropriate for all patients. Because this document incorporated the efforts of...
265 CitationsSource
#1Aimee O. Hersh (UofU: University of Utah)H-Index: 18
#2Sampath Prahalad (Emory University)H-Index: 35
Juvenile idiopathic arthritis (JIA) is the most common chronic inflammatory arthropathy of childhood. Juvenile idiopathic arthritis is believed to be a complex genetic trait influenced by both genetic and environmental factors. Twin and family studies suggest a substantial role for genetic factors in the predisposition to JIA. Describing the genetics is complicated by the heterogeneity of JIA; the International League of Associations for Rheumatology (ILAR) has defined seven categories of JIA ba...
56 CitationsSource
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