Original paper
Co-Administration of Morphine and Naloxone: Histopathological and Biochemical Changes in the Rat Liver
Abstract
Background: Co-administration of opioid agonists and antagonists at low doses has been reported to significantly enhance and/or prolong the analgesic effects and reduce or prevent tolerance to or dependence on opioids. Objectives: The current study aimed at evaluating the naloxone effect on morphine-induced histopathological and hematologic changes in rats. Materials and Mehods: Thirty mature male Wistar rats were categorized into three groups...
Paper Details
Title
Co-Administration of Morphine and Naloxone: Histopathological and Biochemical Changes in the Rat Liver
Published Date
Aug 26, 2020
Volume
9
Issue
3
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Notes
History