Therapeutic strategies for Parkinson’s disease: promising agents in early clinical development

To date, no drug has demonstrated clinically indisputable neuroprotective efficacy in Parkinson's disease (PD). We also have no effective symptomatic treatment for disabling symptoms such as balance problems, and dementia, and we need to improve the efficacy and safety profile of drugs currently used in the management of motor complications.We examine the agents which appear to have most therapeutic promise based on concepts, feasibility in a...