Germline genetic variability in pancreatic cancer risk and prognosis
Abstract
Pancreatic cancer (PC), particularly its most common form, pancreatic ductal adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk factors could in the long term contribute to early diagnosis and mortality reduction. We review the current status of research on germline genetic factors for PC risk. Genome-wide association studies (GWAS) successfully identified common loci convincingly associated with PC risk, an...
Paper Details
Title
Germline genetic variability in pancreatic cancer risk and prognosis
Published Date
Feb 1, 2022
Journal
Volume
79
Pages
105 - 131
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