Corrigendum to: Modeling of reaction-diffusion transport into a core-shell geometry.

Published on Dec 21, 2020in Journal of Theoretical Biology2.327
· DOI :10.1016/J.JTBI.2020.110439
Clarence C. King1
Estimated H-index: 1
(WSU: Washington State University),
Amelia Ann Brown1
Estimated H-index: 1
(WSU: Washington State University)
+ 2 AuthorsScott P. Beckman20
Estimated H-index: 20
(WSU: Washington State University)
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#1Clarence C. King (WSU: Washington State University)H-Index: 1
#2Amelia Ann Brown (WSU: Washington State University)H-Index: 1
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Abstract Fickian diffusion into a core-shell geometry is modeled. The interior core mimics pancreatic Langerhan islets and the exterior shell acts as inert protection. The consumption of oxygen diffusing into the cells is approximated using Michaelis-Menten kinetics. The problem is transformed to dimensionless units and solved numerically. Two regimes are identified, one that is diffusion limited and the other consumption limited. A regression is fit that describes the concentration at the cente...
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