Coronavirus-2019. Consideraciones Generales

Published on Apr 1, 2020
· DOI :10.35366/92866
Martín de Jesús Sánchez-Zúñiga3
Estimated H-index: 3
Raúl Carrillo-Esper10
Estimated H-index: 10
#1Zunyou Wu (CCDC: Chinese Center for Disease Control and Prevention)H-Index: 56
#2Jennifer M. McGoogan (CCDC: Chinese Center for Disease Control and Prevention)H-Index: 17
The Chinese Center for Disease Control and Prevention recently published the largest case series to date of coronavirus disease 2019 (COVID-19) in mainland China (72 314 cases, updated through February 11, 2020). This Viewpoint summarizes key findings from this report and discusses emerging understanding of and lessons from the COVID-19 epidemic.
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#1Chirag Bavishi (Brown University)H-Index: 25
#2Thomas M. Maddox (WashU: Washington University in St. Louis)H-Index: 54
Last. Franz H. Messerli (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 49
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#1Waleed Alhazzani (McMaster University)H-Index: 48
#2Morten Hylander Møller (Copenhagen University Hospital)H-Index: 30
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view all 36 authors...
BACKGROUND: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting thousands of people around the world. Urgent guidance for clinicians caring for the sickest of these patients is needed. METHODS: We formed a panel of 36 experts from 12 countries. All panel members completed the World Health Organization conflict of interest disclosure form. The panel proposed 53 questions that are relevan...
874 CitationsSource
#1Yuefei Jin (Zhengzhou University)H-Index: 11
#2Haiyan Yang (Zhengzhou University)H-Index: 5
Last. Guangcai Duan (Zhengzhou University)H-Index: 9
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The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) in 2002~2003 and Middle East respiratory syndrome (MERS) in 2012 have accelerated our understanding of the epidemiology and pathogenesis of SARS-CoV-2 and the development of therap...
505 CitationsSource
#1Yaseen M. Arabi (National Guard Health Affairs)H-Index: 82
#2Srinivas Murthy (UBC: University of British Columbia)H-Index: 41
Last. Steve Webb (Monash University)H-Index: 13
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the original version of this article unfortunately contained a mistake. there was an error in table one: in the last row, second column the part “still being defined to” should be crossed out. the correct table 1 can be found below. we apologize for the mistake.
18 CitationsSource
: Over the past three months, the world has faced an unprecedented health hazard. The World Health Organization has announced a pandemic infection with an unknown species of coronavirus called SARS-CoV-2. Spreading mainly through the droplet route, the virus causes mild symptoms in the majority of cases, the most common being: fever (80%), dry cough (56%), fatigue (22%) and muscle pain (7%); less common symptoms include a sore throat, a runny nose, diarrhea, hemoptysis and chills. A life-threate...
72 CitationsSource
#1Daniel Batlle (NU: Northwestern University)H-Index: 65
#2Jan Wysocki (NU: Northwestern University)H-Index: 22
Last. Karla J. F. Satchell (NU: Northwestern University)H-Index: 32
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A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019, has spread to other regions of China and to 25 other countries as of January, 2020. It has been known since the 2003 SARS epidemic that the receptor critical for SARS-CoV entry into host cells is the angiotensin-converting enzyme 2 (ACE2). The S1 domain of the spike protein of SARS-CoV attaches the virus to its cellular...
239 CitationsSource
#1Qian Yi Peng (CSU: Central South University)H-Index: 1
#2Xiao Ting Wang (Peking Union Medical College Hospital)H-Index: 1
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391 CitationsSource
#1Aiping Wu (Peking Union Medical College)H-Index: 17
#2Yousong Peng (Hunan University)H-Index: 14
Last. Taijiao Jiang (Peking Union Medical College)H-Index: 21
view all 16 authors...
An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may have caused functional and pathogenic divergence of 2019-nCoV.
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