Recent advances in graphene-family nanomaterials for effective drug delivery and phototherapy.

Published on Jan 2, 2021in Expert Opinion on Drug Delivery4.838
· DOI :10.1080/17425247.2020.1798400
Jiang Cuiping1
Estimated H-index: 1
(Southern Medical University),
Haiyue Zhao1
Estimated H-index: 1
(Southern Medical University)
+ 6 AuthorsQiang Liu6
Estimated H-index: 6
(Southern Medical University)
Sources
Abstract
INTRODUCTION Owing to the unique properties of graphene, including large specific surface area, excellent thermal conductivity, and optical absorption, graphene-family nanomaterials (GFNs) have attracted extensive attention in biomedical applications, particularly in drug delivery and phototherapy. AREAS COVERED In this review, we point out several challenges involved in the clinical application of GFNs. Then, we provide an overview of the most recent publications about GFNs in biomedical applications, including diverse strategies for improving the biocompatibility, specific targeting and stimuli-responsiveness of GFNs for drug delivery, codelivery of drug and gene, photothermal therapy, photodynamic therapy, and multimodal combination therapy. EXPERT OPINION Although the application of GFNs is still in the preclinical stage, rational modification of GFNs with functional elements or making full use of GFNs-based multimodal combination therapy might show great potential in biomedicine for clinical application.
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