Review paper
Neutrophil diversity and plasticity in tumour progression and therapy
Abstract
Neutrophils play a key role in defence against infection and in the activation and regulation of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have emerged as an important component of the tumour microenvironment. Here, they can exert dual functions. TANs can be part of tumour-promoting inflammation by driving angiogenesis, extracellular matrix remodelling, metastasis and immunosuppression. Conversely, neutrophils...
Paper Details
Title
Neutrophil diversity and plasticity in tumour progression and therapy
Published Date
Jul 21, 2020
Journal
Volume
20
Issue
9
Pages
485 - 503