Intensive care medicine

Emergency medicine

Cohort

Cognition

Psychiatry

Cognitive impairment

Telephone interview

Coronavirus disease 2019 (COVID-19)

Infectious disease (medical specialty)

Internal medicine

Sociology

Delirium

Medicine

Disease

Social science

European Geriatric Medicine

To ascertain delirium prevalence and outcomes in COVID-19.We conducted a point-prevalence study in a cohort of COVID-19 inpatients at University College Hospital. Delirium was defined by DSM-IV criteria. The primary outcome was all-cause mortality at 4 weeks; secondary outcomes were physical and cognitive function.In 71 patients (mean age 61, 75% men), 31 (42%) had delirium, of which only 12 (39%) had been recognised by the clinical team. At 4 weeks, 20 (28%) had died, 26 (36%) were interviewed by telephone and 21 (30%) remained as inpatients. Physical function was substantially worse in people after delirium - 50 out of 166 points (95% CI - 83 to - 17, p = 0.01). Mean cognitive scores at follow-up were similar and delirium was not associated with mortality in this sample.Our findings indicate that delirium is common, yet under-recognised. Delirium is associated with functional impairments in the medium term.

Functional and cognitive outcomes after COVID-19 delirium