Mechanism of cAMP-PKA Signaling Pathway Mediated by Shaoyao Gancao Decoction (芍药甘草汤) on Regulation of Aquaporin 5 and Muscarinic Receptor 3 Levels in Sjögren’s Syndrome

OBJECTIVE To investigate the mechanism of cAMP-PKA signaling pathway mediated by Chinese medicine formula Shaoyao Gancao Decoction (, SGD) on the regulation of aquaporin 5 (AQP5) and muscarinic receptor 3 (M3R) levels in Sjogren's syndrome (SS). METHODS Of the 30 mice, 5 were randomly selected as control, and others were used for creating SS model. After successful modeling, mice were randomly divided into 5 groups (n=5 per group) and...