Cyclooxygenases and the cardiovascular system
Volume: 217, Pages: 107624 - 107624
Published: Jan 1, 2021
Abstract
Cyclooxygenase (COX)-1 and COX-2 are centrally important enzymes within the cardiovascular system with a range of diverse, sometimes opposing, functions. Through the production of thromboxane, COX in platelets is a pro-thrombotic enzyme. By contrast, through the production of prostacyclin, COX in endothelial cells is antithrombotic and in the kidney regulates renal function and blood pressure. Drug inhibition of COX within the cardiovascular...
Paper Details
Title
Cyclooxygenases and the cardiovascular system
Published Date
Jan 1, 2021
Volume
217
Pages
107624 - 107624
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