1474-P: Association between Low Birth Weight and ß-Cell Function in Adults without Diabetes from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Based on the fetal origins of diseases hypothesis, adverse intrauterine environment - reflected by low birth weight (LBW) - has been linked to insulin resistance and type 2 diabetes later in life. Whether β cell function reduction could be detected even in middle-aged adults is less investigated. We examined the association of LBW with β cell function and insulin sensitivity. This is a cross-sectional analysis of 2634 ELSA-Brasil participants...