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Original paper

Substance P enhances the local activation of NK1R-expressing c-kit+ cardiac progenitor cells in right atrium of ischemia/reperfusion-injured heart

Volume: 21, Issue: 1
Published: Jun 9, 2020
Abstract
Background Localization of neurokinin 1 receptor (NK 1 R), the endogenous receptor for neuropeptide substance P (SP), has already been described for the right atrium (RA) of the heart. However, the biological role of SP/NK 1 R signal pathways in the RA remains unclear. Sprague-Dawley rats were randomly divided into 4 groups ( n = 22 each); subjected to sham, ischemia/reperfusion-injury (I/R), I/R with 5 nmole/kg SP injection (SP + I/R), and SP +...
Paper Details
Title
Substance P enhances the local activation of NK1R-expressing c-kit+ cardiac progenitor cells in right atrium of ischemia/reperfusion-injured heart
Published Date
Jun 9, 2020
Volume
21
Issue
1
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