Bone morphogenetic protein-2 immobilized polylactic acid nanofiber scaffold via poly dopamine promotes the osteogenic differentiation of bone mesenchymal stem cells

Objective To synthesize poly dopamine (PDA) coated polylactic acid nanofiber (PLLA) scaffold immobilized with bone morphogenetic protein-2 (BMP-2) peptide and evaluate its osteogenetic effects in vitro. Methods The PLLA-PDA-BMP-2 peptide scaffold was set as experiment group. The PLLA-PDA and the PLLA scaffold were set as control group. The X-ray photoelectron spectroscopy (XPS), contact angle viewer, scanning electron microscope (SEM) and...