Breakthroughs in the Use of Inositols for Assisted Reproductive Treatment (ART)

MI and DCI are insulin second messengers, but have different functions. MI is involved primarily in cellular glucose uptake (e.g., the ovary, testis, and epididymis contain high concentrations of MI). By contrast, DCI levels are high in tissues where glycogen is stored (e.g., liver and muscle). In the ovary, MI acts also as a second messenger downstream of follicle-stimulating hormone. MI is involved in cell proliferation and improves oocyte and...