Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation
Abstract
Articular cartilage remains among the most difficult tissues to regenerate due to its poor self-repair capacity. The lysyl oxidase family (LOX; also termed as protein-lysine 6-oxidase), mainly consists of lysyl oxidase (LO) and lysyl oxidase-like 1-4 (LOXL1-LOXL4), has been traditionally defined as cuproenzymes that are essential for stabilization of extracellular matrix, particularly cross-linking of collagen and elastin. LOX is essential in...
Paper Details
Title
Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation
Published Date
Apr 30, 2020
Volume
8
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