A facile synthesis of uniform hollow MIL-125 titanium-based nanoplatform for endosomal esacpe and intracellular drug delivery

Metal-organic-frameworks (MOFs) have been widely used for drug delivery systems due to their high drug loading content and easy modification. But it remains the biggest challenge to exploring biocompatible MOFs with uniform small sizes and well-defined surface chemistry for tumor therapy. Especially, the hollow-structured MIL-125 Titanium (Ti) nano-MOFs have not been prepared for drug carriers. Therefore, we studied a facile approach to...