Antiviral activities of type I interferons to SARS-CoV-2 infection

Volume: 179, Pages: 104811 - 104811
Published: Jul 1, 2020
Abstract
There is an urgent need to identify antivirals to curtail the COVID-19 pandemic. Herein, we report the sensitivity of SARS-CoV-2 to recombinant human interferons α and β (IFNα/β). Treatment with IFN-α or IFN-β at a concentration of 50 international units (IU) per milliliter reduces viral titers by 3.4 log or over 4 log, respectively, in Vero cells. The EC50 of IFN-α and IFN-β treatment is 1.35 IU/ml and 0.76 IU/ml, respectively, in Vero cells....
Paper Details
Title
Antiviral activities of type I interferons to SARS-CoV-2 infection
Published Date
Jul 1, 2020
Volume
179
Pages
104811 - 104811
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.