Neuronal activity increases translocator protein (TSPO) levels

Volume: 26, Issue: 6, Pages: 2025 - 2037
Published: May 12, 2020
Abstract
The mitochondrial protein, translocator protein (TSPO), is a widely used biomarker of neuroinflammation, but its non-selective cellular expression pattern implies roles beyond inflammatory processes. In the present study, we investigated whether neuronal activity modifies TSPO levels in the adult central nervous system. First, we used single-cell RNA sequencing to generate a cellular landscape of basal TSPO gene expression in the hippocampus of...
Paper Details
Title
Neuronal activity increases translocator protein (TSPO) levels
Published Date
May 12, 2020
Volume
26
Issue
6
Pages
2025 - 2037
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