Cressdnaviricota : a Virus Phylum Unifying Seven Families of Rep-Encoding Viruses with Single-Stranded, Circular DNA Genomes

Eukaryotic single-stranded DNA (ssDNA) viruses are classified into 10 families (Table 1), but many remain unclassified (1, 2). Viruses from seven families (Bacilladnaviridae, Circoviridae, Geminiviridae, Genomoviridae, Nanoviridae, Redondoviridae, and Smacoviridae) have small circular genomes, with some encompassing only two genes, encoding the replication initiation protein (Rep) and the capsid protein (3–5). The genomes are replicated by the...