doi.org/10.1016/j.theriogenology.2020.02.036
Original paper

Aberrant DNA and histone methylation during zygotic genome activation in goat cloned embryos

..., Feng Wang
33
Theriogenology2.40
Volume: 148, Pages: 27 - 36
Published: May 1, 2020
Abstract
In somatic cell nuclear transfer (SCNT) embryos, developmental defects first appear at the time of zygotic genome activation (ZGA), a process that is under the control of DNA and histone methylation. However, dynamics of 5-mC and 5-hmC during ZGA differ between porcine and bovine SCNT embryos, and histone methylation during ZGA in goat SCNT embryos remains poorly understood. Therefore, in the present study, we investigated the dynamic changes of...
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Paper Details
Title
Aberrant DNA and histone methylation during zygotic genome activation in goat cloned embryos
DOI
doi.org/10.1016/j.theriogenology.2020.02.036
Published Date
May 1, 2020
Journal
Theriogenology
Volume
148
Pages
27 - 36
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