Detecting TRA-1–60 in Cancer via a Novel Zr-89 Labeled ImmunoPET Imaging Agent
Abstract
TRA-1–60 (TRA) is a cell-surface antigen implicated in drug resistance, relapse, and recurrence. Its expression has been reported in breast, prostate, pancreatic, ovarian tumors, and follicular lymphoma, which paved the development of the therapeutic antibody, Bstrongomab (Bsg), and its drug conjugates. Because patient selection is critical to achieve clinical benefit, a noninvasive imaging agent to select TRA+ lesions in patients is needed....
Paper Details
Title
Detecting TRA-1–60 in Cancer via a Novel Zr-89 Labeled ImmunoPET Imaging Agent
Published Date
Feb 18, 2020
Journal
Volume
17
Issue
4
Pages
1139 - 1147
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Notes
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