Ice-templating of chitosan/agarose porous composite hydrogel with adjustable water-sensitive shape memory property and multi-staged degradation performance

Water-induced shape memory polymers (SMPs) may have important applications in the fields of tissue engineering and biomedicine. However, most of the ideal candidates often suffer from non-biodegradation, weak mechanical strength and random macro-porous structure, which do limit the creativity and dynamism of water-sensitive SPMs. To address above issue, in this study, by incorporating the pH-responsive chitosan (CHIT) into a thermoplastic...