Last. Dmitry V. Shtansky(NUST: National University of Science and Technology)H-Index: 36
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Abstract null null To date, significant progress has been achieved in the development of biomedical superelastic Ti-based alloys with high mechanical properties. In view of the high probability of implant-associated infection, an urgent task is to impart bactericidal properties to the material. Herein, advanced superelastic Ti-18Zr-15Nb alloys were surface-etched in a piranha solution, and then Ag nanoparticles were deposited on their surface using a polyol process. This led to the formation of ...
Abstract null null Deep burns are a common form of trauma worldwide, and they are hard to be cured in a short time and enhance psychological pressure of the patients. How to effectively promote the healing of wounds after burns is a continuing challenge currently faced by burn physicians. Various strategies of promoting wound healing of deep burns have been developed, including gene therapy and growth factor therapy. In this study, we developed a combined therapy using PLGA nanoparticles as carr...
Abstract null null Diabetes is a widely spread disease affecting the quality of life of millions of people around the world and is associated to a higher risk of developing infections in different parts of the body. The reasons why diabetes enhances infection episodes are not entirely clear; in this study our aim was to explore the changes that one of the most frequently pathogenic bacteria undergoes when exposed to hyperglycemia and ketoacidosis conditions. Physical surface properties such as h...
Last. Shangzhong Jin(China Jiliang University)H-Index: 14
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ABSTRACT null null Single-base mutations of Factor V Leiden G1691A and Prothrombin gene G20210A are the main genetic risk factors for inherited thrombotic tendency. The establishment for rapid and efficient detection method is of great significance to the prevention of venous thrombosis. In this work, a multiplexed, highly sensitive and regenerable surface plasmon resonance imaging (SPRi) sensor is described to identify and detect the two pathogenic genes by fixing probes in one-step. The probes...
#1Nuntarat Boonlao(AIT: Asian Institute of Technology)H-Index: 1
#2Uracha Ruktanonchai(NSTDA: National Science and Technology Development Agency)H-Index: 36
Last. Anil Kumar Anal(AIT: Asian Institute of Technology)H-Index: 24
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Abstract null null The consumption of foods rich in antioxidants, vitamins, minerals including carotenoids etc. can boost the immune system to help fight off various infections including SARS- CoV 2 and other viruses. Carotenoids have been gaining sattention particularly in food and pharmaceutical industries owing to their diverse functions including their role as pro-vitamin A activity, potent antioxidant properties, and quenching of reactive oxygen (ROS), such as singlet oxygen and lipid perox...
#2Miyeon Kim(INU: Incheon National University)H-Index: 4
Last. Min Suk Shim(INU: Incheon National University)H-Index: 24
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Abstract null null Sonodynamic therapy, which utilizes ultrasound (US) to produce cytotoxic reactive oxygen species (ROS), can overcome the critical drawbacks of photodynamic therapy, such as limited tissue penetration depth. However, the development of sonosensitizers having superior sonodynamic effects and desirable biocompatibility remains a major challenge. In this study, nanoscale zirconium-based porphyrinic metal organic frameworks (MOFs) (PCN-222) were developed as safe and effective nano...
Abstract null null Nanoparticles (NPs) can be produced via physical, chemical, or biological approaches. Yet, the impact of the synthesis approaches on the environmental fate and effects of NPs is poorly understood. Here, we synthesized AgNPs through chemical and biological approaches (cit-AgNPs and bio-AgNPs), characterized their properties, and toxicities relative to commercially available Ag nanopowder (np-AgNPs) to the clam Mercenaria mercenaria. The chemical synthesis is based on the reduct...
#1Jingyi Liu(WUST: Wuhan University of Science and Technology)
#2Zhoutong Dai(WUST: Wuhan University of Science and Technology)
Last. Xinghua Liao(WUST: Wuhan University of Science and Technology)H-Index: 1
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Abstract null null In order to obtain drug delivery carriers with good stability in blood and high cellular uptake efficiency, carboxyl groups and tertiary amine groups were respectively introduced into polyurethane to synthesize two kinds of amphiphilic polyurethanes with opposite charges (PUC and PUN). Their structures were characterized by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (1H NMR) spectroscopy and gel permeation chromatography (GPC). PUC-PUN co-assemb...
Abstract null null Langmuir monolayers are used to simulate the biological membrane environment, acting as a mimetic system of the outer or the inner membrane leaflet. Herein, we analyze the interaction of membrane models with a partially N-acetylated chitosan (Ch35%) possessing a quasi-ideal random pattern of acetylation, full water solubility up to pH ≈ 8.5 and unusually high weight average molecular weight. Lipid monolayers containing dipalmitoyl phosphatidyl choline (DPPC), dipalmitoyl phosp...
Last. Célia M. Ronconi(UFF: Fluminense Federal University)H-Index: 17
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Abstract null null Two platforms based on reduced graphene oxide (rGO) functionalized with Pluronic® P123 (rGO-P123) and polyethyleneimine – PEI (rGO-PEI) polymers and loaded with amphotericin B (AmB) were fabricated and tested against Leishmania amazonensis, which can cause cutaneous and diffuse cutaneous leishmaniasis. The materials rGO-P123 and rGO-PEI were efficiently loaded with AmB – a polyene antibiotic – which resulted in rGO-P123-AmB (0.078 mg per mg of material) and rGO-PEI-AmB (0.086 ...
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