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doi.org/10.1186/s13063-019-3846-x

Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial

..., Mohamed A. Hussein
10
Trials2.50
Volume: 21, Issue: 1
Published: Jan 3, 2020
Abstract
The MIRACLE trial (MERS-CoV Infection tReated with A Combination of Lopinavir/ritonavir and intErferon-β1b) investigates the efficacy of a combination therapy of lopinavir/ritonavir and recombinant interferon-β1b provided with standard supportive care, compared to placebo provided with standard supportive care, in hospitalized patients with laboratory-confirmed MERS. The MIRACLE trial is designed as a recursive, two-stage, group sequential,...
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Paper Details
Title
Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial
DOI
doi.org/10.1186/s13063-019-3846-x
Published Date
Jan 3, 2020
Journal
Trials
Volume
21
Issue
1
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